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Title:

Assessment of the Tumor-Stroma Ratio and Tumor-Infiltrating Lymphocytes in Colorectal Cancer: Inter-Observer Agreement Evaluation.

Document type:
Journal Article
Author(s):
Kazemi, Azar; Gharib, Masoumeh; Mohamadian Roshan, Nema; Taraz Jamshidi, Shirin; Stögbauer, Fabian; Eslami, Saeid; Schüffler, Peter J
Abstract:
BACKGROUND: To implement the new marker in clinical practice, reliability assessment, validation, and standardization of utilization must be applied. This study evaluated the reliability of tumor-infiltrating lymphocytes (TILs) and tumor-stroma ratio (TSR) assessment through conventional microscopy by comparing observers' estimations. METHODS: Intratumoral and tumor-front stromal TILs, and TSR, were assessed by three pathologists using 86 CRC HE slides. TSR and TILs were categorized using one an...     »
Journal title abbreviation:
Diagnostics (Basel)
Year:
2023
Journal volume:
13
Journal issue:
14
Fulltext / DOI:
doi:10.3390/diagnostics13142339
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37510083
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie (Dr. Mogler komm.)
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