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Title:

Comparison of PD-L1 expression in squamous cell cancer of unknown primary and oropharyngeal squamous cell carcinoma.

Document type:
Journal Article
Author(s):
Schmidl, Benedikt; Voßenkämper, Kim-Aylin; Stark, Leonhard; Boxberg, Melanie; Stögbauer, Fabian; Feigl, Katharina; Winter, Christof; Pickhard, Anja; Wollenberg, Barbara; Wirth, Markus
Abstract:
PURPOSE: The tumorigenesis of squamous cell cancer of unknown primary (SCCUP) in the head and neck area has not been decoded so far, while poor survival rates and limited therapeutic options pose a serious challenge. The aim of this project was to investigate immunological characteristics of SCCUPs and compare them to oropharyngeal squamous cell carcinoma (OPSCC). METHODS: PD-L1 expression (TC) was examined by immunohistochemistry in 50 lymph node metastases of SCCUP and 47 primaries of OPSCC. C...     »
Journal title abbreviation:
Eur Arch Otorhinolaryngol
Year:
2023
Journal volume:
280
Journal issue:
4
Pages contribution:
1991-1997
Fulltext / DOI:
doi:10.1007/s00405-022-07775-z
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/36576530
Print-ISSN:
0937-4477
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie (Dr. Mogler komm.); Institut für Klinische Chemie und Pathobiochemie (Prof. Ruland); Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde (Prof. Wollenberg)
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