The results of this dissertation show impaired exercise capacity and a limitation of the autonomic nervous system in patients with congenital heart disease. Furthermore, evidence regarding the influence of severity and individual subgroups of the heart defects on heart rate variability and an existing association between peak oxygen uptake, representing exercise capacity, and parasympathetic activity could be provided. Especially patients with Fontan circulation suffer from sympathovagal imbalance and show impaired exercise capacity and lung function.
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The results of this dissertation show impaired exercise capacity and a limitation of the autonomic nervous system in patients with congenital heart disease. Furthermore, evidence regarding the influence of severity and individual subgroups of the heart defects on heart rate variability and an existing association between peak oxygen uptake, representing exercise capacity, and parasympathetic activity could be provided. Especially patients with Fontan circulation suffer from sympathovagal imbalan...
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