X-ray nanoCT enables the non-destructive 3D imaging of the internal structures of a specimen with resolutions in the nanometer range. This thesis presents contributions to the advancement of lab-based nanoCT imaging of biological samples. A new nanoCT system, based on a nanofocus source and a single-photon counting detector, is presented. Suitable sample preparation and contrast-enhancement techniques are introduced that enable imaging of biological specimens with high soft-tissue contrast. To assess the potential of this method, applications from the fields of evolutionary biology and histology are presented.
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X-ray nanoCT enables the non-destructive 3D imaging of the internal structures of a specimen with resolutions in the nanometer range. This thesis presents contributions to the advancement of lab-based nanoCT imaging of biological samples. A new nanoCT system, based on a nanofocus source and a single-photon counting detector, is presented. Suitable sample preparation and contrast-enhancement techniques are introduced that enable imaging of biological specimens with high soft-tissue contrast. To...
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