The dissertation was completed as a German-French joint research project (Cotutelle de Thèse) of the Technische Universität München and the Centre de biophysique moléculaire, CNRS UPR 4301, affiliated to the University of Orléans. Royal jelly is produced by the honey bee (Apis mellifera) by absorption and processing of plant pollen and nectar. It plays a key role in the proliferation and immunity of the growing insects and the organisation of their social system. Royal jelly is a potential source of pharmaceutically applicable substances. Selected substance groups from royal jelly were analysed in correlation to their biological functions. The antimicrobial properties of royal jellies of specific botanical and geographical origin and fractions isolated therefrom, were systematically investigated with relevant microorganisms. Using a multitude of physico-chemical and microbiological investigation methods, the antibacterial activities of peptide and protein fractions were proven and further applications were discussed.
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The dissertation was completed as a German-French joint research project (Cotutelle de Thèse) of the Technische Universität München and the Centre de biophysique moléculaire, CNRS UPR 4301, affiliated to the University of Orléans. Royal jelly is produced by the honey bee (Apis mellifera) by absorption and processing of plant pollen and nectar. It plays a key role in the proliferation and immunity of the growing insects and the organisation of their social system. Royal jelly is a potential sourc...
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