20 patients with multiple sclerosis and without apparent motor deficits of the upper extremities were examined with transcranial magnetic stimulation of the primary motor cortex of the hand. In most patients, dysfunctions of the corticospinal motor system and an abnormal cortical inhibition were found. Furthermore, these patients demonstrated an impairment of fine motor movements in a 3D motor analysis. This will be important for the evaluation of the patients´ disability level. In this group of patients, the motor impairment did not correlate with the noticeable electrophysiological abnormalities.
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20 patients with multiple sclerosis and without apparent motor deficits of the upper extremities were examined with transcranial magnetic stimulation of the primary motor cortex of the hand. In most patients, dysfunctions of the corticospinal motor system and an abnormal cortical inhibition were found. Furthermore, these patients demonstrated an impairment of fine motor movements in a 3D motor analysis. This will be important for the evaluation of the patients´ disability level. In this group of...
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