Benutzer: Gast  Login
Weniger Felder
Einfache Suche
Titel:

Myelination generates aberrant ultrastructure that is resolved by microglia.

Dokumenttyp:
Article; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Djannatian, Minou; Radha, Swathi; Weikert, Ulrich; Safaiyan, Shima; Wrede, Christoph; Deichsel, Cassandra; Kislinger, Georg; Rhomberg, Agata; Ruhwedel, Torben; Campbell, Douglas S; van Ham, Tjakko; Schmid, Bettina; Hegermann, Jan; Möbius, Wiebke; Schifferer, Martina; Simons, Mikael
Abstract:
To enable rapid propagation of action potentials, axons are ensheathed by myelin, a multilayered insulating membrane formed by oligodendrocytes. Most of the myelin is generated early in development, resulting in the generation of long-lasting stable membrane structures. Here, we explored structural and dynamic changes in central nervous system myelin during development. To achieve this, we performed an ultrastructural analysis of mouse optic nerves by serial block face scanning electron microsco...     »
Zeitschriftentitel:
J Cell Biol
Jahr:
2023
Band / Volume:
222
Heft / Issue:
3
Volltext / DOI:
doi:10.1083/jcb.202204010
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/36637807
Print-ISSN:
0021-9525
TUM Einrichtung:
657; Lehrstuhl für Zellbiologie des Nervensystems (Prof. Misgeld)
 BibTeX