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Titel:

An optimized culture system for efficient derivation of porcine expanded potential stem cells from preimplantation embryos and by reprogramming somatic cells.

Dokumenttyp:
Journal Article; Review
Autor(en):
Ruan, Degong; Xuan, Yiyi; Tam, Timothy Theodore Ka Ki; Li, ZhuoXuan; Wang, Xiao; Xu, Shao; Herrmann, Doris; Niemann, Heiner; Lai, Liangxue; Gao, Xuefei; Nowak-Imialek, Monika; Liu, Pentao
Abstract:
Pigs share anatomical and physiological traits with humans and can serve as a large-animal model for translational medicine. Bona fide porcine pluripotent stem cells (PSCs) could facilitate testing cell and drug therapies. Agriculture and biotechnology may benefit from the ability to produce immune cells for studying animal infectious diseases and to readily edit the porcine genome in stem cells. Isolating porcine PSCs from preimplantation embryos has been intensively attempted over the past dec...     »
Zeitschriftentitel:
Nat Protoc
Jahr:
2024
Band / Volume:
19
Heft / Issue:
6
Seitenangaben Beitrag:
1710-1749
Volltext / DOI:
doi:10.1038/s41596-024-00958-4
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/38509352
Print-ISSN:
1754-2189
TUM Einrichtung:
Professur für Regenerative Medizin bei Kardiovaskulären Erkrankungen (Prof. Moretti)
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