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Title:

Association of retinal vessel pathology and brain atrophy in relapsing-remitting multiple sclerosis.

Document type:
Observational Study; Journal Article
Author(s):
Romahn, Eva Feodora; Wiltgen, Tun; Bussas, Matthias; Aly, Lilian; Wicklein, Rebecca; Noll, Christina; Berthele, Achim; Dehmelt, Vera; Mardin, Christian; Zimmer, Claus; Korn, Thomas; Hemmer, Bernhard; Kirschke, Jan S; Mühlau, Mark; Knier, Benjamin
Abstract:
BACKGROUND: Optical coherence tomography angiography (OCTA) allows non-invasive assessment of retinal vessel structures. Thinning and loss of retinal vessels is evident in eyes of patients with multiple sclerosis (MS) and might be associated with a proinflammatory disease phenotype and worse prognosis. We investigated whether changes of the retinal vasculature are linked to brain atrophy and disability in MS. MATERIAL AND METHODS: This study includes one longitudinal observational cohort (n=79)...     »
Journal title abbreviation:
Front Immunol
Year:
2023
Journal volume:
14
Fulltext / DOI:
doi:10.3389/fimmu.2023.1284986
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/38090586
Print-ISSN:
1664-3224
TUM Institution:
Klinik und Poliklinik für Neurologie (Prof. Hemmer); Molekulare Immunologie (Prof. Knolle); Professur für Neuroradiologie (Prof. Zimmer)
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