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Titel:

Influenza A Virus Infection Reactivates Human Endogenous Retroviruses Associated with Modulation of Antiviral Immunity.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Liu, Hengyuan; Bergant, Valter; Frishman, Goar; Ruepp, Andreas; Pichlmair, Andreas; Vincendeau, Michelle; Frishman, Dmitrij
Abstract:
Human endogenous retrovirus (HERVs), normally silenced by methylation or mutations, can be reactivated by multiple environmental factors, including infections with exogenous viruses. In this work, we investigated the transcriptional activity of HERVs in human A549 cells infected by two wild-type (PR8M, SC35M) and one mutated (SC35MΔNS1) strains of Influenza A virus (IAVs). We found that the majority of differentially expressed HERVs (DEHERVS) and genes (DEGs) were up-regulated in the infected ce...     »
Zeitschriftentitel:
Viruses
Jahr:
2022
Band / Volume:
14
Heft / Issue:
7
Volltext / DOI:
doi:10.3390/v14071591
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/35891571
Print-ISSN:
1999-4915
TUM Einrichtung:
Institut für Virologie (Prof. Protzer)
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