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Title:

Drug-based optical agents: infiltrating clinics at lower risk.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Review; Correction
Author(s):
Scheuer, W; van Dam, GM; Dobosz, M; Schwaiger, M; Ntziachristos, V
Abstract:
Fluorescent agents with specificity to cellular and subcellular moieties present promise for enhancing diagnostics and theranostics, yet challenges associated with regulatory approvals of experimental agents stifle the clinical translation. As a result, targeted fluorescent agents have remained predominantly as preclinical imaging tools. We discuss the potential of using optically labeled drugs to accelerate the clinical acceptance of optical and optoacoustic agents, in analogy to nuclear medici...     »
Journal title abbreviation:
Sci Transl Med
Year:
2012
Journal volume:
4
Journal issue:
134
Pages contribution:
134ps11
Language:
eng
Fulltext / DOI:
doi:10.1126/scitranslmed.3003572
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22593172
Print-ISSN:
1946-6234
TUM Institution:
Klinik und Poliklinik für Nuklearmedizin; Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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