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Titel:

REM sleep-active hypothalamic neurons may contribute to hippocampal social-memory consolidation.

Dokumenttyp:
Journal Article
Autor(en):
Qin, Han; Fu, Ling; Jian, Tingliang; Jin, Wenjun; Liang, Mengru; Li, Jin; Chen, Qianwei; Yang, Xinyu; Du, Haoran; Liao, Xiang; Zhang, Kuan; Wang, Rui; Liang, Shanshan; Yao, Jiwei; Hu, Bo; Ren, Shuancheng; Zhang, Chunqing; Wang, Yanjiang; Hu, Zhian; Jia, Hongbo; Konnerth, Arthur; Chen, Xiaowei
Abstract:
The hippocampal CA2 region plays a key role in social memory. The encoding of such memory involves afferent activity from the hypothalamic supramammillary nucleus (SuM) to CA2. However, the neuronal circuits required for consolidation of freshly encoded social memory remain unknown. Here, we used circuit-specific optical and single-cell electrophysiological recordings in mice to explore the role of sleep in social memory consolidation and its underlying circuit mechanism. We found that SuM neuro...     »
Zeitschriftentitel:
Neuron
Jahr:
2022
Band / Volume:
110
Heft / Issue:
23
Seitenangaben Beitrag:
4000-4014.e6
Volltext / DOI:
doi:10.1016/j.neuron.2022.09.004
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/36272414
Print-ISSN:
0896-6273
TUM Einrichtung:
Institut für Neurowissenschaften
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