Ecker, Veronika;Brandmeier, Lisa;Stumpf, Martina;Giansanti, Piero;Moreira, Aida Varela;Pfeuffer, Lisa;Fens, Marcel H A M;Lu, Junyan;Kuster, Bernhard;Engleitner, Thomas;Heidegger, Simon;Rad, Roland;Ringshausen, Ingo;Zenz, Thorsten;Wendtner, Clemens-Martin;Müschen, Markus;Jellusova, Julia;Ruland, Jürgen;Buchner, Maike
Negative feedback regulation of MAPK signaling is an important driver of chronic lymphocytic leukemia progression.
Cell Rep
2023
42
10

Andersen, Line Lykke;Huang, Yiqi;Urban, Christian;Oubraham, Lila;Winheim, Elena;Stafford, Che;Nagl, Dennis;O'Duill, Fionan;Ebert, Thomas;Engleitner, Thomas;Paludan, Søren Riis;Krug, Anne;Rad, Roland;Hornung, Veit;Pichlmair, Andreas
Systematic P2Y receptor survey identifies P2Y11 as modulator of immune responses and virus replication in macrophages.
EMBO J
2023
42
23

Frank, Daria;Patnana, Pradeep Kumar;Vorwerk, Jan;Mao, Lianghao;Gopal, Lavanya Mokada;Jung, Noelle;Hennig, Thorben;Ruhnke, Leo;Frenz, Joris Maximillian;Kuppusamy, Maithreyan;Autry, Robert;Wei, Lanying;Sun, Kaiyan;Mohammed Ahmed, Helal Mohammed;Künstner, Axel;Busch, Hauke;Müller, Heiko;Hutter, Stephan;Hoermann, Gregor;Liu, Longlong;Xie, Xiaoqing;Al-Matary, Yahya;Nimmagadda, Subbaiah Chary;Cano, Fiorella Charles;Heuser, Michael;Thol, Felicitas;Göhring, Gudrun;Steinemann, Doris;Thomale, Jürgen;Leitner, Theo;Fischer, Anja;Rad, Roland;Röllig, Christoph;Altmann, Heidi;Kunadt, Desiree;Berdel, Wolfgang E;Hüve, Jana;Neumann, Felix;Klingauf, Jürgen;Calderon, Virginie;Opalka, Bertram;Dührsen, Ulrich;Rosenbauer, Frank;Dugas, Martin;Varghese, Julian;Reinhardt, Hans Christian;von Bubnoff, Nikolas;Möröy, Tarik;Lenz, Georg;Batcha, Aarif M N;Giorgi, Marianna;Selvam, Murugan;Wang, Eunice;McWeeney, Shannon K;Tyner, Jeffrey W;Stölzel, Friedrich;Mann, Matthias;Jayavelu, Ashok Kumar;Khandanpour, Cyrus
Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy.
Blood
2023
142
25
2175-2191

Heidegger, Simon;Stritzke, Florian;Dahl, Sarah;Daßler-Plenker, Juliane;Joachim, Laura;Buschmann, Dominik;Fan, Kaiji;Sauer, Carolin M;Ludwig, Nils;Winter, Christof;Enssle, Stefan;Li, Suqi;Perl, Markus;Görgens, André;Haas, Tobias;Orberg, Erik Thiele;Göttert, Sascha;Wölfel, Catherine;Engleitner, Thomas;Cortés-Ciriano, Isidro;Rad, Roland;Herr, Wolfgang;Giebel, Bernd;Ruland, Jürgen;Bassermann, Florian;Coch, Christoph;Hartmann, Gunther;Poeck, Hendrik
Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy.
Cell Rep Med
2023
4
9

Bergant, Valter;Schnepf, Daniel;de Andrade Krätzig, Niklas;Hubel, Philipp;Urban, Christian;Engleitner, Thomas;Dijkman, Ronald;Ryffel, Bernhard;Steiger, Katja;Knolle, Percy A;Kochs, Georg;Rad, Roland;Staeheli, Peter;Pichlmair, Andreas
mRNA 3'UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus.
Nat Commun
2023
14
1

Tretter, Celina;de Andrade Krätzig, Niklas;Pecoraro, Matteo;Lange, Sebastian;Seifert, Philipp;von Frankenberg, Clara;Untch, Johannes;Zuleger, Gabriela;Wilhelm, Mathias;Zolg, Daniel P;Dreyer, Florian S;Bräunlein, Eva;Engleitner, Thomas;Uhrig, Sebastian;Boxberg, Melanie;Steiger, Katja;Slotta-Huspenina, Julia;Ochsenreither, Sebastian;von Bubnoff, Nikolas;Bauer, Sebastian;Boerries, Melanie;Jost, Philipp J;Schenck, Kristina;Dresing, Iska;Bassermann, Florian;Friess, Helmut;Reim, Daniel;Grützmann, Konrad;Pfütze, Katrin;Klink, Barbara;Schröck, Evelin;Haller, Bernhard;Kuster, Bernhard;Mann, Matthias;Weichert, Wilko;Fröhling, Stefan;Rad, Roland;Hiltensperger, Michael;Krackhardt, Angela M
Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification.
Nat Commun
2023
14
1

Wahida, Adam;Schmaderer, Christoph;Büttner-Herold, Maike;Branca, Caterina;Donakonda, Sainitin;Haberfellner, Flora;Torrez, Carlos;Schmitz, Jessica;Schulze, Tobias;Seibt, Tobias;Öllinger, Rupert;Engleitner, Thomas;Haller, Bernhard;Steiger, Katja;Günthner, Roman;Lorenz, Georg;Yabal, Monica;Bachmann, Quirin;Braunisch, Matthias C;Moog, Philipp;Matevossian, Edouard;Aßfalg, Volker;Thorban, Stefan;Renders, Lutz;Späth, Martin R;Müller, Roman-Ulrich;Stippel, Dirk L;Weichert, Wilko;Slotta-Huspenina, Julia;von Vietinghoff, Sibylle;Viklicky, Ondrej;Green, Douglas R;Rad, Roland;Amann, Kerstin;Linkermann, Andreas;Bräsen, Jan Hinrich;Heemann, Uwe;Kemmner, Stephan
High RIPK3 expression is associated with a higher risk of early kidney transplant failure.
iScience
2023
26
10

Linnerbauer, Mathias;Beyer, Tobias;Nirschl, Lucy;Farrenkopf, Daniel;Lößlein, Lena;Vandrey, Oliver;Peter, Anne;Tsaktanis, Thanos;Kebir, Hania;Laplaud, David;Oellinger, Rupert;Engleitner, Thomas;Alvarez, Jorge Ivan;Rad, Roland;Korn, Thomas;Hemmer, Bernhard;Quintana, Francisco J;Rothhammer, Veit
PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation.
Nat Commun
2023
14
1

Beck, Christina;Ramanujam, Deepak;Vaccarello, Paula;Widenmeyer, Florenc;Feuerherd, Martin;Cheng, Cho-Chin;Bomhard, Anton;Abikeeva, Tatiana;Schädler, Julia;Sperhake, Jan-Peter;Graw, Matthias;Safi, Seyer;Hoffmann, Hans;Staab-Weijnitz, Claudia A;Rad, Roland;Protzer, Ulrike;Frischmuth, Thomas;Engelhardt, Stefan
Trimannose-coupled antimiR-21 for macrophage-targeted inhalation treatment of acute inflammatory lung damage.
Nat Commun
2023
14
1

Zhang, Le;Wirth, Matthias;Patra, Upayan;Stroh, Jacob;Isaakidis, Konstandina;Rieger, Leonie;Kossatz, Susanne;Milanovic, Maja;Zang, Chuanbing;Demel, Uta;Keiten-Schmitz, Jan;Wagner, Kristina;Steiger, Katja;Rad, Roland;Bassermann, Florian;Müller, Stefan;Keller, Ulrich;Schick, Markus
Actionable loss of SLF2 drives B-cell lymphomagenesis and impairs the DNA damage response.
EMBO Mol Med
2023
15
9