Kuhn, Laura B;Valentin, Stefanie;Stojanovic, Kristina;Strobl, Daniel C;Babushku, Tea;Wang, Yan;Rambold, Ursula;Scheffler, Laura;Grath, Sonja;John-Robbert, Dorothy;Blum, Helmut;Feuchtinger, Annette;Blutke, Andreas;Weih, Falk;Kitamura, Daisuke;Rad, Roland;Strobl, Lothar J;Zimber-Strobl, Ursula
RelB contributes to the survival, migration and lymphomagenesis of B cells with constitutively active CD40 signaling.
Front Immunol
2022
13

Mahajan, Ujjwal M;Oehrle, Bettina;Sirtl, Simon;Alnatsha, Ahmed;Goni, Elisabetta;Regel, Ivonne;Beyer, Georg;Vornhülz, Marlies;Vielhauer, Jakob;Chromik, Ansgar;Bahra, Markus;Klein, Fritz;Uhl, Waldemar;Fahlbusch, Tim;Distler, Marius;Weitz, Jürgen;Grützmann, Robert;Pilarsky, Christian;Weiss, Frank Ulrich;Adam, M Gordian;Neoptolemos, John P;Kalthoff, Holger;Rad, Roland;Christiansen, Nicole;Bethan, Bianca;Kamlage, Beate;Lerch, Markus M;Mayerle, Julia
Independent Validation and Assay Standardization of Improved Metabolic Biomarker Signature to Differentiate Pancreatic Ductal Adenocarcinoma From Chronic Pancreatitis.
Gastroenterology
2022
163
5
1407-1422

Haimovici, Aladin;Höfer, Christoph;Badr, Mohamed Tarek;Bavafaye Haghighi, Elham;Amer, Tarek;Boerries, Melanie;Bronsert, Peter;Glavynskyi, Ievgen;Fanfone, Deborah;Ichim, Gabriel;Thilmany, Nico;Weber, Arnim;Brummer, Tilman;Spohr, Corinna;Öllinger, Rupert;Janssen, Klaus-Peter;Rad, Roland;Häcker, Georg
Spontaneous activity of the mitochondrial apoptosis pathway drives chromosomal defects, the appearance of micronuclei and cancer metastasis through the Caspase-Activated DNAse.
Cell Death Dis
2022
13
4

Donne, Romain;Saroul-Ainama, Maëva;Cordier, Pierre;Hammoutene, Adel;Kabore, Christelle;Stadler, Mira;Nemazanyy, Ivan;Galy-Fauroux, Isabelle;Herrag, Mounia;Riedl, Tobias;Chansel-Da Cruz, Marie;Caruso, Stefano;Bonnafous, Stéphanie;Öllinger, Rupert;Rad, Roland;Unger, Kristian;Tran, Albert;Couty, Jean-Pierre;Gual, Philippe;Paradis, Valérie;Celton-Morizur, Séverine;Heikenwalder, Mathias;Revy, Patrick;Desdouets, Chantal
Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD.
Dev Cell
2022
57
14
1728-1741.e6

Metzger, Rebecca;Winter, Lis;Bouznad, Nassim;Garzetti, Debora;von Armansperg, Benedikt;Rokavec, Matjaz;Lutz, Konstantin;Schäfer, Yvonne;Krebs, Sabrina;Winheim, Elena;Friedrich, Verena;Matzek, Dana;Öllinger, Rupert;Rad, Roland;Stecher, Bärbel;Hermeking, Heiko;Brocker, Thomas;Krug, Anne B
CCL17 Promotes Colitis-Associated Tumorigenesis Dependent on the Microbiota.
J Immunol
2022
209
11
2227-2238

Ben Khaled, Najib;Hammer, Katharina;Ye, Liangtao;Alnatsha, Ahmed;Widholz, Sebastian A;Piseddu, Ignazio;Sirtl, Simon;Schneider, Julia;Munker, Stefan;Mahajan, Ujjwal Mukund;Montero, Juan José;Griger, Joscha;Mayerle, Julia;Reiter, Florian P;De Toni, Enrico N
TRAIL Receptor Targeting Agents Potentiate PARP Inhibitor Efficacy in Pancreatic Cancer Independently of BRCA2 Mutation Status.
Cancers (Basel)
2022
14
21

Paulmann, Carmen;Spallek, Ria;Karpiuk, Oleksandra;Heider, Michael;Schäffer, Isabell;Zecha, Jana;Klaeger, Susan;Walzik, Michaela;Öllinger, Rupert;Engleitner, Thomas;Wirth, Matthias;Keller, Ulrich;Krönke, Jan;Rudelius, Martina;Kossatz, Susanne;Rad, Roland;Kuster, Bernhard;Bassermann, Florian
The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma.
EMBO J
2022
41
20

Sie, Christopher;Kant, Ravi;Peter, Christian;Muschaweckh, Andreas;Pfaller, Monika;Nirschl, Lucy;Moreno, Helena Domínguez;Chadimová, Tereza;Lepennetier, Gildas;Kuhlmann, Tanja;Öllinger, Rupert;Engleitner, Thomas;Rad, Roland;Korn, Thomas
IL-24 intrinsically regulates Th17 cell pathogenicity in mice.
J Exp Med
2022
219
8

Mitsdoerffer, Meike;Aly, Lilian;Barz, Melanie;Engleitner, Thomas;Sie, Christopher;Delbridge, Claire;Lepennetier, Gildas;Öllinger, Rupert;Pfaller, Monika;Wiestler, Benedikt;Rad, Roland;Meyer, Bernhard;Knier, Benjamin;Schmidt-Graf, Friederike;Gempt, Jens;Korn, Thomas
The glioblastoma multiforme tumor site promotes the commitment of tumor-infiltrating lymphocytes to the TH17 lineage in humans.
Proc Natl Acad Sci U S A
2022
119
34

Randriamanantsoa, S.;Papargyriou, A.;Maurer, H. C.;Peschke, K.;Schuster, M.;Zecchin, G.;Steiger, K.;Oellinger, R.;Saur, D.;Scheel, C.;Rad, R.;Hannezo, E.;Reichert, M.;Bausch, A. R.
Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids
Nat Commun
2022
13
1