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Titel:

Anti-inflammatory chemoprevention attenuates the phenotype in a mouse model of esophageal adenocarcinoma.

Dokumenttyp:
Article; Journal Article; Research Support, N.I.H., Extramural
Autor(en):
Baumeister, Theresa; Ingermann, Jonas; Marcazzan, Sabrina; Fang, Hsin-Yu; Oellinger, Rupert; Rad, Roland; Engleitner, Thomas; Kleigrewe, Karin; Anand, Akanksha; Strangmann, Julia; Schmid, Roland M; Wang, Timothy C; Quante, Michael
Abstract:
Barrett's esophagus (BE) is the main known precursor condition of esophageal adenocarcinoma (EAC). BE is defined by the presence of metaplasia above the normal squamous columnar junction and has mainly been attributed to gastroesophageal reflux disease and chronic reflux esophagitis. Thus, the rising incidence of EAC in the Western world is probably mediated by chronic esophageal inflammation, secondary to gastroesophageal reflux disease in combination with environmental risk factors such as a W...     »
Zeitschriftentitel:
Carcinogenesis
Jahr:
2021
Band / Volume:
42
Heft / Issue:
8
Seitenangaben Beitrag:
1068-1078
Volltext / DOI:
doi:10.1093/carcin/bgab032
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33878160
Print-ISSN:
0143-3334
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik (Gastroenterologie); Professur für Translationale gastroenterologische Onkologie (Prof. Rad)
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