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Titel:

A Single-Cell Perspective on Memory T-Cell Differentiation.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Review
Autor(en):
Kretschmer, Lorenz; Busch, Dirk H; Buchholz, Veit R
Abstract:
Memory differentiation of CD4 and CD8 T-cell populations has been extensively studied and many key molecular players and transcriptional networks have been identified. But how regulatory principles, identified on this population level, translate to immune responses that originate from single antigen-specific T cells is only now being elucidated. Here, we provide a short summary of the approaches used for mapping the fate of individual T cells and their progeny in vivo. We then highlight which ma...     »
Zeitschriftentitel:
Cold Spring Harb Perspect Biol
Jahr:
2021
Band / Volume:
13
Heft / Issue:
9
Volltext / DOI:
doi:10.1101/cshperspect.a038067
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33903160
Print-ISSN:
1943-0264
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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