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Title:

Label-free analytic histology of carotid atherosclerosis by mid-infrared optoacoustic microscopy.

Document type:
Zeitschriftenaufsatz
Author(s):
Visscher, Mirjam; Pleitez, Miguel A; Van Gaalen, Kim; Nieuwenhuizen-Bakker, Ingeborg M; Ntziachristos, Vasilis; Van Soest, Gijs
Abstract:
BACKGROUND AND AIMS: Analysis of atherosclerotic plaque composition is a vital tool for unraveling the pathological metabolic processes that contribute to plaque growth. METHODS: We visualize the constitution of human carotid plaques by mid-infrared optoacoustic microscopy (MiROM), a method for label-free analytic histology that requires minimal tissue preparation, rapidly yielding large field-of-view en-face images with a resolution of a few micrometers. We imaged endarterectomy specimens (n =...     »
Journal title:
Photoacoustics
Journal title abbreviation:
Photoacoustics
Year:
2022
Journal volume:
26
Fulltext / DOI:
doi:10.1016/j.pacs.2022.100354
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/35465607
WWW:
https://www.sciencedirect.com/science/article/pii/S2213597922000234
Print-ISSN:
2213-5979
TUM Institution:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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