User: Guest  Login
More Searchfields
Simple search
Title:

Disorders of histone methylation: Molecular basis and clinical syndromes.

Document type:
Journal Article; Review
Author(s):
Al Ojaimi, Mode; Banimortada, Bashar J; Othman, Amna; Riedhammer, Korbinian M; Almannai, Mohammed; El-Hattab, Ayman W
Abstract:
Epigenetic modifications of DNA and histone tails are essential for gene expression regulation. They play an essential role in neurodevelopment as nervous system development is a complex process requiring a dynamic pattern of gene expression. Histone methylation is one of the vital epigenetic regulators and mostly occurs on lysine residues of histones H3 and H4. Histone methylation is catalyzed by two sets of enzymes: histone lysine methyltransferases (KMTs) and histone lysine demethylases (KDMs...     »
Journal title abbreviation:
Clin Genet
Year:
2022
Journal volume:
102
Journal issue:
3
Pages contribution:
169-181
Fulltext / DOI:
doi:10.1111/cge.14181
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/35713103
Print-ISSN:
0009-9163
TUM Institution:
Professur für Nephrologie (Prof. Heemann)
 BibTeX