The aim of this work is to reconstitute in vitro model systems that allow to shed light on the interaction between the cell’s cytoskeleton and lipid membranes. We use two model systems for cytoskeletal dynamics, i.e., the gliding assay and a microtubule-based active fluid, and two model systems of membranes, i.e., supported lipid bilayers and giant unilamellar vesicles, combining them appropriately to learn more about how, on the one hand, active motion of cytoskeletal filaments can be affected by the presence of a membrane and, on the other hand, how the membrane reacts to active forces.
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The aim of this work is to reconstitute in vitro model systems that allow to shed light on the interaction between the cell’s cytoskeleton and lipid membranes. We use two model systems for cytoskeletal dynamics, i.e., the gliding assay and a microtubule-based active fluid, and two model systems of membranes, i.e., supported lipid bilayers and giant unilamellar vesicles, combining them appropriately to learn more about how, on the one hand, active motion of cytoskeletal filaments can be affected...
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