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Titel:

β2 Integrin Signaling Cascade in Neutrophils: More Than a Single Function.

Dokumenttyp:
Journal Article; Review; Research Support, Non-U.S. Gov't
Autor(en):
Bouti, Panagiota; Webbers, Steven D S; Fagerholm, Susanna C; Alon, Ronen; Moser, Markus; Matlung, Hanke L; Kuijpers, Taco W
Abstract:
Neutrophils are the most prevalent leukocytes in the human body. They have a pivotal role in the innate immune response against invading bacterial and fungal pathogens, while recent emerging evidence also demonstrates their role in cancer progression and anti-tumor responses. The efficient execution of many neutrophil effector responses requires the presence of β2 integrins, in particular CD11a/CD18 or CD11b/CD18 heterodimers. Although extensively studied at the molecular level, the exact signal...     »
Zeitschriftentitel:
Front Immunol
Jahr:
2020
Band / Volume:
11
Volltext / DOI:
doi:10.3389/fimmu.2020.619925
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33679708
Print-ISSN:
1664-3224
TUM Einrichtung:
Experimentelle Hämatologie (Prof. Schmidt-Supprian)
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