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Deep Learning Reveals Cancer Metastasis and Therapeutic Antibody Targeting in the Entire Body.
Cell
2019
179
7
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Fabian, Alexander;Stegner, Simon;Miarka, Lauritz;Zimmermann, Johannes;Lenk, Lennart;Rahn, Sascha;Buttlar, Jann;Viol, Fabrice;Knaack, Hendrike;Esser, Daniela;Schäuble, Sascha;Großmann, Peter;Marinos, Georgios;Häsler, Robert;Mikulits, Wolfgang;Saur, Dieter;Kaleta, Christoph;Schäfer, Heiner;Sebens, Susanne
Metastasis of pancreatic cancer: An uninflamed liver micromilieu controls cell growth and cancer stem cell properties by oxidative phosphorylation in pancreatic ductal epithelial cells.
Cancer Lett
2019
453
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Besnard, Antoine;Gao, Yuan;TaeWoo Kim, Michael;Twarkowski, Hannah;Reed, Alexander Keith;Langberg, Tomer;Feng, Wendy;Xu, Xiangmin;Saur, Dieter;Zweifel, Larry S;Davison, Ian;Sahay, Amar
Dorsolateral septum somatostatin interneurons gate mobility to calibrate context-specific behavioral fear responses.
Nat Neurosci
2019
22
3
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Murakami, Shigekazu;Nemazanyy, Ivan;White, Shannon M;Chen, Hengye;Nguyen, Chan D K;Graham, Garrett T;Saur, Dieter;Pende, Mario;Yi, Chunling
A Yap-Myc-Sox2-p53 Regulatory Network Dictates Metabolic Homeostasis and Differentiation in Kras-Driven Pancreatic Ductal Adenocarcinomas.
Dev Cell
2019
51
1
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Sun, Qi;Lee, Wendy;Mohri, Yasuaki;Takeo, Makoto;Lim, Chae Ho;Xu, Xiaowei;Myung, Peggy;Atit, Radhika P;Taketo, M Mark;Moubarak, Rana S;Schober, Markus;Osman, Iman;Gay, Denise L;Saur, Dieter;Nishimura, Emi K;Ito, Mayumi
A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease.
Nat Commun
2019
10
1

Kohlruss, Meike;Grosser, Bianca;Krenauer, Marie;Slotta-Huspenina, Julia;Jesinghaus, Moritz;Blank, Susanne;Novotny, Alexander;Reiche, Magdalena;Schmidt, Thomas;Ismani, Liridona;Hapfelmeier, Alexander;Mathias, Daniel;Meyer, Petra;Gaida, Matthias M;Bauer, Lukas;Ott, Katja;Weichert, Wilko;Keller, Gisela
Prognostic implication of molecular subtypes and response to neoadjuvant chemotherapy in 760 gastric carcinomas: role of Epstein-Barr virus infection and high- and low-microsatellite instability.
J Pathol Clin Res
2019
5
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Münch, Stefan;Pigorsch, Steffi U;Deve?ka, Michal;Dapper, Hendrik;Feith, Marcus;Friess, Helmut;Weichert, Wilko;Jesinghaus, Moritz;Braren, Rickmer;Combs, Stephanie E;Habermehl, Daniel
Neoadjuvant versus definitive chemoradiation in patients with squamous cell carcinoma of the esophagus.
Radiat Oncol
2019
14
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Falcomatà, Chiara;Bärthel, Stefanie;Schneider, Günter;Saur, Dieter;Veltkamp, Christian
Deciphering the universe of genetic context-dependencies using mouse models of cancer.
Curr Opin Genet Dev
2019
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PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice.
Nat Commun
2019
10
1

Jesinghaus, Moritz;Boxberg, Melanie;Wilhelm, Dirk;Münch, Stefan;Dapper, Hendrik;Quante, Michael;Schlag, Christoph;Lange, Sebastian;Budczies, Jan;Konukiewitz, Björn;Mollenhauer, Martin;Schlitter, Anna Melissa;Becker, Karl Friedrich;Feith, Marcus;Friess, Helmut;Steiger, Katja;Combs, Stephanie E;Weichert, Wilko
Post-neoadjuvant cellular dissociation grading based on tumour budding and cell nest size is associated with therapy response and survival in oesophageal squamous cell carcinoma.
Br J Cancer
2019
121
12
1050-1057