Atatri, Sura;Meyers, Marianne;Klein, Eliane;Brunner, Valentina;Tschurtschenthaler, Markus;Letellier, Elisabeth
Protocol for sub-mucosal orthotopic injection of organoids into murine colon to study tumor growth and metastasis.
STAR Protoc
2025
6
2

Tschurtschenthaler, Markus
Dietary modulation of the gut phageome: a cross-kingdom dialogue in Crohn's disease.
Gut
2025
75
1
4-5

Kakavand, Nassim;Xiang, Hang;Laue, Georg;Mekdoud, Taous;Welz, Lina;Silva, Miguel Gomes;Bernardes, Joana P;Ito, Go;van den Bossche, Silke;Kugler, Julia;Tran, Florian;Ossysek, Alexander;Imm, Simon;Hinrichsen, Finn;Jesinghaus, Moritz;Kaser, Arthur;Blumberg, Richard;Adolph, Timon E;Schreiber, Stefan;Tschurtschenthaler, Markus;Rosenstiel, Philip;Aden, Konrad
Atg16l1 and Xbp1 cooperatively protect from transcription-associated mutagenesis and small intestinal carcinogenesis.
Oncogene
2025
44
45
4413-4426

Kos, Tina;Saur, Dieter
Breaking down KRAS: small-molecule degraders for cancer therapy.
Signal Transduct Target Ther
2025
10
1

Järke, Lea;Weber-Stiehl, Saskia;Shima, Kensuke;Moors, Karlis Arturs;Genth, Jerome;Schuran, Fenja Amrei;Best, Lena;Tschurtschenthaler, Markus;Flemer, Burkhardt;Lüschen, Silke;Röcken, Christoph;Tholey, Andreas;Kaleta, Christoph;Rupp, Jan;Rosenstiel, Philip;Sommer, Felix
Deletion of epithelial HKDC1 decelerates cellular proliferation and impairs mitochondrial function of tumorous epithelial cells thereby protecting from intestinal carcinogenesis.
Cancer Commun (Lond)
2025
45
7
722-727

Kawai, Munenori;Fukuda, Akihisa;Ikeda, Munehiro;Iimori, Kei;Mizukoshi, Kenta;Iwane, Kosuke;Yamakawa, Go;Omatsu, Mayuki;Namikawa, Mio;Sono, Makoto;Masuda, Tomonori;Fukunaga, Yuichi;Nagao, Munemasa;Araki, Osamu;Yoshikawa, Takaaki;Ogawa, Satoshi;Hiramatsu, Yukiko;Tsuda, Motoyuki;Maruno, Takahisa;Nakanishi, Yuki;Saur, Dieter;Tsuruyama, Tatsuaki;Masui, Toshihiko;Hatano, Etsuro;Seno, Hiroshi
Polybromo 1/vimentin axis dictates tumor grade, epithelial-mesenchymal transition, and metastasis in pancreatic cancer.
J Clin Invest
2025
135
11

Zur, Raphaëlle Toledano;Zurinam, Shiran Didi;Radman, Maria;Funaro Balouka, Elia;Borodianskiy-Shteinberg, Tatiana;Saur, Dieter;Cohen, Cyrille J
Hexokinase2-engineered T cells display increased anti-tumor function.
Front Immunol
2025
16

Köse, Hazal;Schneeweis, Christian;Putze, Philipp;Contreras, Constanza Tapia;Ferreiro, Laura;Witte, Leonie;Deidda, Ilaria;Herzberg, Frederik;Ebert, Sophie;Jakubik, Juraj;Moldaner, Leoni;Todorovic, Jovan;Träger, Isabelle;Zang, Chuanbing;Demel, Uta M;Hessmann, Elisabeth;Kirchner, Marieluise;Rhein, Simone;Hoffmann, Jens;Tatarova, Zuzana;Ghadimi, Michael;Saur, Dieter;Kappert, Kai;Mertins, Philipp;Schneider, Günter;Keller, Ulrich;Wirth, Matthias
Targeting Mutual Dependence of Phosphatidylinositol-3-Kinase α/δ and Small Ubiquitin-Like Modifier Signaling in Pancreatic Cancer.
Gastroenterology
2026
170
2
315-329

Krauss, Theresa;Gürcinar, Ibrahim Halil;Bourquain, Ulrike;Hieber, Maren;Krohmer, Evelyn N;Wu, Nan;Tokalov, Sergey;Goess, Rüdiger;Reyes, Carmen Mota;Saur, Dieter;Friess, Helmut;Ceyhan, Güralp O;Demir, Ihsan Ekin;Safak, Okan
Pancreatic cancer cells infiltrate nerves through TGFbeta1-driven perineural epithelial-to-mesenchymal-like transdifferentiation.
Neoplasia
2025
60

Heger, Klaus;Masjedi, Ali;Yeroslaviz, Assa;Zeng, Theodor;Baygün, Seren;Vicente-Luque, Angela;Lien, Chia-I;Osswald, Lena;Saur, Dieter;Kovacs, Daniel;Schmidt-Supprian, Marc
Serous Cavity Mast Cells Depend on the ROQUIN Paralogs.
Eur J Immunol
2025
55
12