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Titel:

The Role of Autophagy in Pancreatic Cancer: From Bench to the Dark Bedside.

Dokumenttyp:
Journal Article; Review
Autor(en):
Görgülü, Kıvanç; Diakopoulos, Kalliope N; Kaya-Aksoy, Ezgi; Ciecielski, Katrin J; Ai, Jiaoyu; Lesina, Marina; Algül, Hana
Abstract:
Pancreatic cancer is one of the deadliest cancer types urgently requiring effective therapeutic strategies. Autophagy occurs in several compartments of pancreatic cancer tissue including cancer cells, cancer associated fibroblasts, and immune cells where it can be subjected to a multitude of stimulatory and inhibitory signals fine-tuning its activity. Therefore, the effects of autophagy on pancreatic carcinogenesis and progression differ in a stage and context dependent manner. In the initiation...     »
Zeitschriftentitel:
Cells
Jahr:
2020
Band / Volume:
9
Heft / Issue:
4
Volltext / DOI:
doi:10.3390/cells9041063
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/32344698
TUM Einrichtung:
Lehrstuhl für Tumormetabolismus (Prof. Algül)
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