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Notch-Induced Myeloid Reprogramming in Spontaneous Pancreatic Ductal Adenocarcinoma by Dual Genetic Targeting.
Cancer Res
2018
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Tschurtschenthaler, Markus;Adolph, Timon Erik
The Selective Autophagy Receptor Optineurin in Crohn's Disease.
Front Immunol
2018
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Aden, Konrad;Tran, Florian;Ito, Go;Sheibani-Tezerji, Raheleh;Lipinski, Simone;Kuiper, Jan W;Tschurtschenthaler, Markus;Saveljeva, Svetlana;Bhattacharyya, Joya;Häsler, Robert;Bartsch, Kareen;Luzius, Anne;Jentzsch, Marlene;Falk-Paulsen, Maren;Stengel, Stephanie T;Welz, Lina;Schwarzer, Robin;Rabe, Björn;Barchet, Winfried;Krautwald, Stefan;Hartmann, Gunther;Pasparakis, Manolis;Blumberg, Richard S;Schreiber, Stefan;Kaser, Arthur;Rosenstiel, Philip
ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING.
J Exp Med
2018
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Klein, S.;Seidler, B.;Schmid, R. M.;Reichert, M.;Schneider, G.;Saur, D.
Interstitial cells of Cajal and smooth muscle cells derive from a common precursor at a late embryonic and early postnatal stage
Neurogastroenterol Motil
2018
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Kwak, Mingyu;Ninche, Ninche;Klein, Sabine;Saur, Dieter;Ghazizadeh, Soosan
c-Kit+ Cells in Adult Salivary Glands do not Function as Tissue Stem Cells.
Sci Rep
2018
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Chen, Yang;LeBleu, Valerie S;Carstens, Julienne L;Sugimoto, Hikaru;Zheng, Xiaofeng;Malasi, Shruti;Saur, Dieter;Kalluri, Raghu
Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program.
EMBO Mol Med
2018
10
10

Wang, Lele;Zhao, Linlin;Wei, Guo;Saur, Dieter;Seidler, Barbara;Wang, Junyan;Wang, Chuanxin;Qi, Tonggang
Homoharringtonine could induce quick protein synthesis of PSMD11 through activating MEK1/ERK1/2 signaling pathway in pancreatic cancer cells.
J Cell Biochem
2018
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Vicinanza, Carla;Aquila, Iolanda;Cianflone, Eleonora;Scalise, Mariangela;Marino, Fabiola;Mancuso, Teresa;Fumagalli, Francesca;Giovannone, Emilia Dora;Cristiano, Francesca;Iaccino, Enrico;Marotta, Pina;Torella, Annalaura;Latini, Roberto;Agosti, Valter;Veltri, Pierangelo;Urbanek, Konrad;Isidori, Andrea M;Saur, Dieter;Indolfi, Ciro;Nadal-Ginard, Bernardo;Torella, Daniele
Kitcre knock-in mice fail to fate-map cardiac stem cells.
Nature
2018
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E1-E5

Roesner, T.;Lechler, C.;Birgit, K. -E.;Steiger, K.;Mogler, C.;Saur, D.;Sage, J.;Schmid, R. M.;Ehmer, U.
KRAS-dependent AKT signaling drives hepatocyte proliferation to promote tumor development in a genetic model of liver cancer
J Hepatol
2018
68
S689-S689

Tsuda, Motoyuki;Fukuda, Akihisa;Roy, Nilotpal;Hiramatsu, Yukiko;Leonhardt, Laura;Kakiuchi, Nobuyuki;Hoyer, Kaja;Ogawa, Satoshi;Goto, Norihiro;Ikuta, Kozo;Kimura, Yoshito;Matsumoto, Yoshihide;Takada, Yutaka;Yoshioka, Takuto;Maruno, Takahisa;Yamaga, Yuichi;Kim, Grace E;Akiyama, Haruhiko;Ogawa, Seishi;Wright, Christopher V;Saur, Dieter;Takaori, Kyoichi;Uemoto, Shinji;Hebrok, Matthias;Chiba, Tsutomu;Seno, Hiroshi
The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis.
J Clin Invest
2018
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