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Titel:

PSMA PET Imaging in Glioblastoma: A Preclinical Evaluation and Theranostic Outlook.

Dokumenttyp:
Journal Article
Autor(en):
Kirchner, Maximilian A; Holzgreve, Adrien; Brendel, Matthias; Orth, Michael; Ruf, Viktoria C; Steiger, Katja; Pötter, Dennis; Gold, Lukas; Unterrainer, Marcus; Mittlmeier, Lena M; Barci, Enio; Kälin, Roland E; Glass, Rainer; Lindner, Simon; Kaiser, Lena; Maas, Jessica; von Baumgarten, Louisa; Ilhan, Harun; Belka, Claus; Notni, Johannes; Bartenstein, Peter; Lauber, Kirsten; Albert, Nathalie L
Abstract:
Background: Prostate specific membrane antigen (PSMA) PET imaging has recently gained attention in glioblastoma (GBM) patients as a potential theranostic target for PSMA radioligand therapy. However, PSMA PET has not yet been established in a murine GBM model. Our goal was to investigate the potential of PSMA PET imaging in the syngeneic GL261 GBM model and to give an outlook regarding the potential of PMSA radioligand therapy in this model. Methods: We performed an 18F-PSMA-1007 PET study in th...     »
Zeitschriftentitel:
Front Oncol
Jahr:
2021
Band / Volume:
11
Volltext / DOI:
doi:10.3389/fonc.2021.774017
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/34869017
Print-ISSN:
2234-943X
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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