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Title:

Bridging the Species Gap: Morphological and Molecular Comparison of Feline and Human Intestinal Carcinomas.

Document type:
Journal Article
Author(s):
Groll, Tanja; Schopf, Franziska; Denk, Daniela; Mogler, Carolin; Schwittlick, Ulrike; Aupperle-Lellbach, Heike; Sarker, Sabrina Rim Jahan; Pfarr, Nicole; Weichert, Wilko; Matiasek, Kaspar; Jesinghaus, Moritz; Steiger, Katja
Abstract:
Limited availability of in vivo experimental models for invasive colorectal cancer (CRC) including metastasis and high tumor budding activity is a major problem in colorectal cancer research. In order to compare feline and human intestinal carcinomas, tumors of 49 cats were histologically subtyped, graded and further characterized according to the human WHO classification. Subsequently, feline tumors were compared to a cohort of 1004 human CRC cases. Feline intestinal tumors closely resembled th...     »
Journal title abbreviation:
Cancers (Basel)
Year:
2021
Journal volume:
13
Journal issue:
23
Fulltext / DOI:
doi:10.3390/cancers13235941
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/34885050
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie; Lehrstuhl für Experimentelle Tumortherapie (Prof. Saur)
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