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Titel:

Bridging the Species Gap: Morphological and Molecular Comparison of Feline and Human Intestinal Carcinomas.

Dokumenttyp:
Journal Article
Autor(en):
Groll, Tanja; Schopf, Franziska; Denk, Daniela; Mogler, Carolin; Schwittlick, Ulrike; Aupperle-Lellbach, Heike; Sarker, Sabrina Rim Jahan; Pfarr, Nicole; Weichert, Wilko; Matiasek, Kaspar; Jesinghaus, Moritz; Steiger, Katja
Abstract:
Limited availability of in vivo experimental models for invasive colorectal cancer (CRC) including metastasis and high tumor budding activity is a major problem in colorectal cancer research. In order to compare feline and human intestinal carcinomas, tumors of 49 cats were histologically subtyped, graded and further characterized according to the human WHO classification. Subsequently, feline tumors were compared to a cohort of 1004 human CRC cases. Feline intestinal tumors closely resembled th...     »
Zeitschriftentitel:
Cancers (Basel)
Jahr:
2021
Band / Volume:
13
Heft / Issue:
23
Volltext / DOI:
doi:10.3390/cancers13235941
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/34885050
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie; Lehrstuhl für Experimentelle Tumortherapie (Prof. Saur)
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