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Titel:

Iron-Sequestering Nanocompartments as Multiplexed Electron Microscopy Gene Reporters

Dokumenttyp:
Article
Autor(en):
Sigmund, Felix; Pettinger, Susanne; Kube, Massimo; Schneider, Fabian; Schifferer, Martina; Schneider, Steffen; Efremova, Maria V.; Pujo-Marti, Jesus; Aichler, Michaela; Walch, Axel; Misgeld, Thomas; Dietz, Hendrik; Westmeyer, Gil G.
Abstract:
Multicolored gene reporters for light microscopy are indispensable for biomedical research, but equivalent genetic tools for electron microscopy (EM) are still rare despite the increasing importance of nanometer resolution for reverse engineering of molecular machinery and reliable mapping of cellular circuits. We here introduce the fully genetic encapsulin/cargo system of Quasibacillus thermotolerans (Qt), which in combination with the recently characterized encapsulin system from Myxococcus xa...     »
Zeitschriftentitel:
ACS Nano
Jahr:
2019
Band / Volume:
13
Heft / Issue:
7
Seitenangaben Beitrag:
8114-8123
Volltext / DOI:
doi:10.1021/acsnano.9b03140
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31194509
Print-ISSN:
1936-0851
TUM Einrichtung:
Lehrstuhl für Zellbiologie des Nervensystems (Prof. Misgeld)
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