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SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4.
Nat Commun
2018
9
1
5378

Knier, Benjamin;Hiltensperger, Michael;Sie, Christopher;Aly, Lilian;Lepennetier, Gildas;Engleitner, Thomas;Garg, Garima;Muschaweckh, Andreas;Mitsdörffer, Meike;Koedel, Uwe;Höchst, Bastian;Knolle, Percy;Gunzer, Matthias;Hemmer, Bernhard;Rad, Roland;Merkler, Doron;Korn, Thomas
Myeloid-derived suppressor cells control B cell accumulation in the central nervous system during autoimmunity.
Nat Immunol
2018
19
12
1341-1351

Mahajan, Ujjwal Mukund;Langhoff, Eno;Goni, Elisabetta;Costello, Eithne;Greenhalf, William;Halloran, Christopher;Ormanns, Steffen;Kruger, Stephan;Boeck, Stefan;Ribback, Silvia;Beyer, Georg;Dombroswki, Frank;Weiss, Frank-Ulrich;Neoptolemos, John P;Werner, Jens;D'Haese, Jan G;Bazhin, Alexandr;Peterhansl, Julian;Pichlmeier, Svenja;Büchler, Markus W;Kleeff, Jörg;Ganeh, Paula;Sendler, Matthias;Palmer, Daniel H;Kohlmann, Thomas;Rad, Roland;Regel, Ivonne;Lerch, Markus M;Mayerle, Julia
Immune Cell and Stromal Signature Associated With Progression-Free Survival of Patients With Resected Pancreatic Ductal Adenocarcinoma.
Gastroenterology
2018
155
5
1625-1639.e2

Preussner, Jens;Zhong, Jiasheng;Sreenivasan, Krishnamoorthy;Günther, Stefan;Engleitner, Thomas;Künne, Carsten;Glatzel, Markus;Rad, Roland;Looso, Mario;Braun, Thomas;Kim, Johnny
Oncogenic Amplification of Zygotic Dux Factors in Regenerating p53-Deficient Muscle Stem Cells Defines a Molecular Cancer Subtype.
Cell Stem Cell
2018
23
6
794-805.e4

Stangl, Stefan;Tei, Lorenzo;De Rose, Francesco;Reder, Sybille;Martinelli, Jonathan;Sievert, Wolfgang;Shevtsov, Maxim;Öllinger, Rupert;Rad, Roland;Schwaiger, Markus;D'Alessandria, Calogero;Multhoff, Gabriele
Preclinical Evaluation of the Hsp70 Peptide Tracer TPP-PEG24-DFO[89Zr] for Tumor-Specific PET/CT Imaging.
Cancer Res
2018
78
21
6268-6281

Mueller, Sebastian;Engleitner, Thomas;Maresch, Roman;Zukowska, Magdalena;Lange, Sebastian;Kaltenbacher, Thorsten;Konukiewitz, Björn;Öllinger, Rupert;Zwiebel, Maximilian;Strong, Alex;Yen, Hsi-Yu;Banerjee, Ruby;Louzada, Sandra;Fu, Beiyuan;Seidler, Barbara;Götzfried, Juliana;Schuck, Kathleen;Hassan, Zonera;Arbeiter, Andreas;Schönhuber, Nina;Klein, Sabine;Veltkamp, Christian;Friedrich, Mathias;Rad, Lena;Barenboim, Maxim;Ziegenhain, Christoph;Hess, Julia;Dovey, Oliver M;Eser, Stefan;Parekh, Swati;Constantino-Casas, Fernando;de la Rosa, Jorge;Sierra, Marta I;Fraga, Mario;Mayerle, Julia;Klöppel, Günter;Cadiñanos, Juan;Liu, Pentao;Vassiliou, George;Weichert, Wilko;Steiger, Katja;Enard, Wolfgang;Schmid, Roland M;Yang, Fengtang;Unger, Kristian;Schneider, Günter;Varela, Ignacio;Bradley, Allan;Saur, Dieter;Rad, Roland
Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes.
Nature
2018
554
7690
62-68

Hassan, Zonera;Schneeweis, Christian;Wirth, Matthias;Veltkamp, Christian;Dantes, Zahra;Feuerecker, Benedikt;Ceyhan, Güralp O;Knauer, Shirley K;Weichert, Wilko;Schmid, Roland M;Stauber, Roland;Arlt, Alexander;Krämer, Oliver H;Rad, Roland;Reichert, Maximilian;Saur, Dieter;Schneider, Günter
MTOR inhibitor-based combination therapies for pancreatic cancer.
Br J Cancer
2018
118
3
366-377

Wartewig, Tim;Kurgyis, Zsuzsanna;Keppler, Selina;Pechloff, Konstanze;Hameister, Erik;Öllinger, Rupert;Maresch, Roman;Buch, Thorsten;Steiger, Katja;Winter, Christof;Rad, Roland;Ruland, Jürgen
Erratum: PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis.
Nature
2018
553
7687
238