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Titel:

Antioxidant Versus Pro-Apoptotic Effects of Mushroom-Enriched Diets on Mitochondria in Liver Disease.

Dokumenttyp:
Journal Article; Review
Autor(en):
Fontes, Adriana; Alemany-Pagès, Mireia; Oliveira, Paulo J; Ramalho-Santos, João; Zischka, Hans; Azul, Anabela Marisa
Abstract:
Mitochondria play a central role in non-alcoholic fatty liver disease (NAFLD) progression and in the control of cell death signalling during the progression to hepatocellular carcinoma (HCC). Associated with the metabolic syndrome, NAFLD is mostly driven by insulin-resistant white adipose tissue lipolysis that results in an increased hepatic fatty acid influx and the ectopic accumulation of fat in the liver. Upregulation of beta-oxidation as one compensatory mechanism leads to an increase in mit...     »
Zeitschriftentitel:
Int J Mol Sci
Jahr:
2019
Band / Volume:
20
Heft / Issue:
16
Volltext / DOI:
doi:10.3390/ijms20163987
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31426291
Print-ISSN:
1422-0067
TUM Einrichtung:
Institut für Toxikologie und Umwelthygiene
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