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Title:

Antioxidant Versus Pro-Apoptotic Effects of Mushroom-Enriched Diets on Mitochondria in Liver Disease.

Document type:
Journal Article; Review
Author(s):
Fontes, Adriana; Alemany-Pagès, Mireia; Oliveira, Paulo J; Ramalho-Santos, João; Zischka, Hans; Azul, Anabela Marisa
Abstract:
Mitochondria play a central role in non-alcoholic fatty liver disease (NAFLD) progression and in the control of cell death signalling during the progression to hepatocellular carcinoma (HCC). Associated with the metabolic syndrome, NAFLD is mostly driven by insulin-resistant white adipose tissue lipolysis that results in an increased hepatic fatty acid influx and the ectopic accumulation of fat in the liver. Upregulation of beta-oxidation as one compensatory mechanism leads to an increase in mit...     »
Journal title abbreviation:
Int J Mol Sci
Year:
2019
Journal volume:
20
Journal issue:
16
Fulltext / DOI:
doi:10.3390/ijms20163987
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/31426291
Print-ISSN:
1422-0067
TUM Institution:
Institut für Toxikologie und Umwelthygiene
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