The conditions of cell rupturing and viability loss of D. salina cells in different hydrodynamic setups were experimentally identified, and relevant measures of sensitivity to hydrodynamic stress were obtained. The tested methodology has a broad applicability regarding cell types and hydrodynamic stress conditions. Additionally, the issues of comparing different hydrodynamic setups were examined, and a new population balance model was presented, connecting cell rupture and viability loss to the heterogeneity of cell populations.
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The conditions of cell rupturing and viability loss of D. salina cells in different hydrodynamic setups were experimentally identified, and relevant measures of sensitivity to hydrodynamic stress were obtained. The tested methodology has a broad applicability regarding cell types and hydrodynamic stress conditions. Additionally, the issues of comparing different hydrodynamic setups were examined, and a new population balance model was presented, connecting cell rupture and viability loss to the...
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