Performance Limitations in Heart Transplant Recipients.
Dokumenttyp:
Journal Article
Autor(en):
Tucker, Wesley J; Beaudry, Rhys I; Samuel, T Jake; Nelson, Michael D; Halle, Martin; Baggish, Aaron L; Haykowsky, Mark J
Abstract:
We hypothesize that the reduced peak aerobic power (peak V˙O2) after heart transplantation is due to impaired cardiovascular and skeletal muscle function, and its improvement with short-term (≤1 yr) exercise training is primarily due to favorable skeletal muscle adaptations. Furthermore, the increased peak V˙O2 with long-term (>2 yr) training is primarily mediated by cardiac (sympathetic) reinnervation.