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Title:

The logistics of myelin biogenesis in the central nervous system.

Document type:
Journal Article; Review; Review
Author(s):
Snaidero, Nicolas; Simons, Mikael
Abstract:
Rapid nerve conduction depends on myelin, but not all axons in the central nervous system (CNS) are myelinated to the same extent. Here, we review our current understanding of the biology of myelin biogenesis in the CNS. We focus on how the different steps of myelination are interconnected and how distinct patterns of myelin are generated. Possibly, a "basal" mode of myelination is laying the groundwork in areas devoted to basic homeostasis early in development, whereas a "targeted" mode generat...     »
Journal title abbreviation:
Glia
Year:
2017
Journal volume:
65
Journal issue:
7
Pages contribution:
1021-1031
Language:
eng
Fulltext / DOI:
doi:10.1002/glia.23116
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28168748
Print-ISSN:
0894-1491
TUM Institution:
Lehrstuhl für Zellbiologie des Nervensystems (Prof. Misgeld)
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