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Title:

Altered Synaptic Membrane Retrieval after Strong Stimulation of Cerebellar Granule Neurons in Cyclic GMP-Dependent Protein Kinase II (cGKII) Knockout Mice.

Document type:
Journal Article
Author(s):
Collado-Alsina, Andrea; Hofmann, Franz; Sánchez-Prieto, José; Torres, Magdalena
Abstract:
The nitric oxide (NO)/cyclic guanosine monophosphate (cGMP)/cGMP-dependent protein kinase (cGK) signaling pathway regulates the clustering and the recruitment of proteins and vesicles to the synapse, thereby adjusting the exoendocytic cycle to the intensity of activity. Accordingly, this pathway can accelerate endocytosis following large-scale exocytosis, and pre-synaptic cGK type II (cGKII) plays a major role in this process, controlling the homeostatic balance of vesicle exocytosis and endocyt...     »
Journal title abbreviation:
Int J Mol Sci
Year:
2017
Journal volume:
18
Journal issue:
11
Language:
eng
Fulltext / DOI:
doi:10.3390/ijms18112281
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29084181
Print-ISSN:
1422-0067
TUM Institution:
Institut für Pharmakologie und Toxikologie
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