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Titel:

NeuBtracker-imaging neurobehavioral dynamics in freely behaving fish.

Dokumenttyp:
Journal Article; Article
Autor(en):
Symvoulidis, Panagiotis; Lauri, Antonella; Stefanoiu, Anca; Cappetta, Michele; Schneider, Steffen; Jia, Hongbo; Stelzl, Anja; Koch, Maximilian; Perez, Carlos Cruz; Myklatun, Ahne; Renninger, Sabine; Chmyrov, Andriy; Lasser, Tobias; Wurst, Wolfgang; Ntziachristos, Vasilis; Westmeyer, Gil G
Abstract:
A long-standing objective in neuroscience has been to image distributed neuronal activity in freely behaving animals. Here we introduce NeuBtracker, a tracking microscope for simultaneous imaging of neuronal activity and behavior of freely swimming fluorescent reporter fish. We showcase the value of NeuBtracker for screening neurostimulants with respect to their combined neuronal and behavioral effects and for determining spontaneous and stimulus-induced spatiotemporal patterns of neuronal activ...     »
Zeitschriftentitel:
Nat Methods
Jahr:
2017
Band / Volume:
14
Heft / Issue:
11
Seitenangaben Beitrag:
1079-1082
Sprache:
eng
Volltext / DOI:
doi:10.1038/nmeth.4459
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28967889
Print-ISSN:
1548-7091
TUM Einrichtung:
Klinik und Poliklinik für Nuklearmedizin; Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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