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Title:

EGFR and Cortactin: Markers for potential double target therapy in oral squamous cell carcinoma.

Document type:
Journal Article
Author(s):
Bissinger, Oliver; Kolk, Andreas; Drecoll, Enken; Straub, Melanie; Lutz, Christina; Wolff, Klaus-Dietrich; Götz, Carolin
Abstract:
Survival periods of patients following surgical therapy of oral squamous cell carcinoma (OSCC) have previously been demonstrated to decrease over recent decades. Epidermal growth factor receptor (EGFR) and Cortactin are molecular markers that are important in tumour progression and development, and interact within the EGF pathway. Although EGFR antibody therapy exists, sufficient efforts for increased survival are still lacking due to the present limited response rates. The aim of the present st...     »
Journal title abbreviation:
Exp Ther Med
Year:
2017
Journal volume:
14
Journal issue:
5
Pages contribution:
4620-4626
Language:
eng
Fulltext / DOI:
doi:10.3892/etm.2017.5120
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29201160
Print-ISSN:
1792-0981
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
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