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- Title:
DNA-Nanostructure-Gold-Nanorod Hybrids for Enhanced In Vivo Optoacoustic Imaging and Photothermal Therapy.
- Document type:
- Journal Article; Journal Article
- Author(s):
- Du, Yang; Jiang, Qiao; Beziere, Nicolas; Song, Linlin; Zhang, Qian; Peng, Dong; Chi, Chongwei; Yang, Xin; Guo, Hongbo; Diot, Gael; Ntziachristos, Vasilis; Ding, Baoquan; Tian, Jie
- Abstract:
- A functional cancer theranostic nanoplatform is developed, specifically tailored toward the optoacoustic modality by combining gold nanorods with DNA nanostructures (D-AuNR). DNA origami is used as an efficient delivery vehicle owing to its prominent tumor-targeting property. The D-AuNR hybrids display an enhanced tumor diagnostic sensitivity by improved optoacoustic imaging and excellent photothermal therapeutic properties in vivo.
- Journal title abbreviation:
- Adv Mater Deerfield
- Year:
- 2016
- Journal volume:
- 28
- Journal issue:
- 45
- Pages contribution:
- 10000-10007
- Language:
- eng
- Fulltext / DOI:
- doi:10.1002/adma.201601710
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/27679425
- Print-ISSN:
- 0935-9648
- TUM Institution:
- Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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