DNA-Nanostructure-Gold-Nanorod Hybrids for Enhanced In Vivo Optoacoustic Imaging and Photothermal Therapy.

Titel:: DNA-Nanostructure-Gold-Nanorod Hybrids for Enhanced In Vivo Optoacoustic Imaging and Photothermal Therapy.
Dokumenttyp:: Journal Article; Journal Article
Autor(en):: Du, Yang; Jiang, Qiao; Beziere, Nicolas; Song, Linlin; Zhang, Qian; Peng, Dong; Chi, Chongwei; Yang, Xin; Guo, Hongbo; Diot, Gael; Ntziachristos, Vasilis; Ding, Baoquan; Tian, Jie
Abstract:: A functional cancer theranostic nanoplatform is developed, specifically tailored toward the optoacoustic modality by combining gold nanorods with DNA nanostructures (D-AuNR). DNA origami is used as an efficient delivery vehicle owing to its prominent tumor-targeting property. The D-AuNR hybrids display an enhanced tumor diagnostic sensitivity by improved optoacoustic imaging and excellent photothermal therapeutic properties in vivo.
Zeitschriftentitel:: Adv Mater Deerfield
Jahr:: 2016
Band / Volume:: 28
Heft / Issue:: 45
Seitenangaben Beitrag:: 10000-10007
Sprache:: eng
Volltext / DOI:: doi:10.1002/adma.201601710
PubMed:: http://view.ncbi.nlm.nih.gov/pubmed/27679425
Print-ISSN:: 0935-9648
TUM Einrichtung:: Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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