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Title:

Response assessment with the CXCR4-directed positron emission tomography tracer [(68)Ga]Pentixafor in a patient with extranodal marginal zone lymphoma of the orbital cavities.

Document type:
Journal Article; Article
Author(s):
Herhaus, Peter; Habringer, Stefan; Vag, Tibor; Steiger, Katja; Slotta-Huspenina, Julia; Gerngroß, Carlos; Wiestler, Benedikt; Wester, Hans-Jürgen; Schwaiger, Markus; Keller, Ulrich
Abstract:
CXCR4 belongs to the family of chemokine receptors. Together with its sole known ligand CXCL12 (SDF-1alpha), it has a pivotal role during organogenesis and for homing of hematopoietic stem cells. CXCR4 is overexpressed in various malignancies, and this is often associated with poor prognosis. Therefore, molecular imaging of CXCR4 bears a great potential for diagnostics and selecting patients for CXCR4-directed therapies. The CXCR4-directed positron emission tomography (PET) tracer [(68)Ga]Pentix...     »
Journal title abbreviation:
EJNMMI Res
Year:
2017
Journal volume:
7
Journal issue:
1
Pages contribution:
51
Language:
eng
Fulltext / DOI:
doi:10.1186/s13550-017-0294-z
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28577295
Print-ISSN:
2191-219X
TUM Institution:
Fachgebiet Neuroradiologie (Prof. Zimmer); III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie); Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für Nuklearmedizin
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