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Titel:

Transarterial Administration of Oncolytic Viruses for Locoregional Therapy of Orthotopic HCC in Rats.

Dokumenttyp:
Journal Article; 110
Autor(en):
Altomonte, Jennifer; Muñoz-Álvarez, Kim A; Shinozaki, Katsunori; Baumgartner, Christine; Kaissis, Georgios; Braren, Rickmer; Ebert, Oliver
Abstract:
Hepatocellular carcinoma (HCC) is a disease with limited treatment options and poor prognosis. In recent years, oncolytic virotherapies have proven themselves to be potentially powerful tools to fight malignancy. Due to the unique dual blood supply in the liver, it is possible to apply therapies locally to orthotopic liver tumors, which are predominantly fed by arterial blood flow. We have previously demonstrated that hepatic arterial delivery of oncolytic viruses results in safe and efficient t...     »
Zeitschriftentitel:
J Vis Exp
Jahr:
2016
Heft / Issue:
110
Sprache:
eng
Volltext / DOI:
doi:10.3791/53757
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27167921
Print-ISSN:
1940-087X
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik (Gastroenterologie); Kliniken und Institute
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