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Title:

The Helicobacter pylori Type IV Secretion System Encoded by the cag Pathogenicity Island: Architecture, Function, and Signaling.

Document type:
Journal Article
Author(s):
Backert, Steffen; Haas, Rainer; Gerhard, Markus; Naumann, Michael
Abstract:
Various gram-negative pathogens express type IV secretion systems (T4SSs) which translocate bacterial virulence factors into host target cells to hijack cellular processes for their own benefit and causing disease. The pathology of Helicobacter pylori, the causative agent of chronic gastritis, peptic ulcer disease, and gastric cancer in humans, strongly depends on a T4SS encoded by the cag pathogenicity island (cagPAI). This T4SS represents a pilus-like structure and a membrane-spanning complex....     »
Journal title abbreviation:
Curr Top Microbiol Immunol
Year:
2017
Journal volume:
413
Pages contribution:
187-220
Language:
eng
Fulltext / DOI:
doi:10.1007/978-3-319-75241-9_8
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29536360
Print-ISSN:
0070-217X
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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