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Title:

Lymphotoxin ? receptor signalling executes Helicobacter pylori-driven gastric inflammation in a T4SS-dependent manner.

Document type:
Journal Article
Author(s):
Mejías-Luque, Raquel; Zoller, Jessica; Anderl, Florian; Loew-Gil, Elena; Vieth, Michael; Adler, Thure; Engler, Daniela B; Urban, Sabine; Browning, Jeffrey L; Müller, Anne; Gerhard, Markus; Heikenwälder, Mathias
Abstract:
Lymphotoxin ? receptor (LT?R) signalling has been implicated in inflammation-associated tumour development in different tissues. We have analysed the role of LT?R and alternative NF-?B signalling in Helicobacter pylori-mediated gastric inflammation and pathology.We analysed several ligands and receptors of the alternative NF-?B pathway, RelB, p52 nuclear translocation and target genes in tissue samples of H. pylori-infected patients with different degrees of gastritis or early gastric tumours by...     »
Journal title abbreviation:
Gut
Year:
2017
Journal volume:
66
Journal issue:
8
Pages contribution:
1369-1381
Language:
eng
Fulltext / DOI:
doi:10.1136/gutjnl-2015-310783
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27196595
Print-ISSN:
0017-5749
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene; Institut für Virologie
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