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Titel:

EGFR immunohistochemistry as biomarker for antibody-based therapy of squamous NSCLC - Experience from the first ring trial of the German Quality Assurance Initiative for Pathology (QuIP®).

Dokumenttyp:
Journal Article
Autor(en):
Petersen, Iver; Dietel, Manfred; Geilenkeuser, Wolf J; Mireskandari, Masoud; Weichert, Wilko; Steiger, Katja; Scheel, Andreas H; Büttner, Reinhard; Schirmacher, Peter; Warth, Arne; Lasitschka, Felix; Schildhaus, Hans-Ulrich; Kirchner, Thomas; Reu, Simone; Kreipe, Hans; Länger, Florian; Tiemann, Markus; Schulte, Christoph; Jöhrens, Korinna
Abstract:
EGFR and its downstream signaling pathway are important targets for cancer therapy. Recently, the monoclonal anti-EGFR antibody Necitumumab in combination with gemcitabine and cisplatin was approved (EMA/14106/2016) for first-line treatment of squamous non-small cell carcinoma (SqNSCLC). Eligibility was restricted to cases with positive EGFR expression. In this context, a ring trial of the Quality Assurance Initiative for Pathology (QuIP®) was launched to prepare the German pathology community f...     »
Zeitschriftentitel:
Pathol Res Pract
Jahr:
2017
Band / Volume:
213
Heft / Issue:
12
Seitenangaben Beitrag:
1530-1535
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.prp.2017.09.021
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29108919
Print-ISSN:
0344-0338
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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