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Titel:

An inwardly rectifying whole cell current induced by Gq-coupled receptors.

Dokumenttyp:
Journal Article; Article
Autor(en):
Buchholz, B; Tauber, R; Steffl, D; Walz, G; Köttgen, M
Abstract:
Ca(2+) influx across the plasma membrane after stimulation of G protein-coupled receptors is important for many physiological functions. Here we studied the regulation of an inwardly rectifying whole cell current and its putative role in Ca(2+) entry in Xenopus oocytes. Expression of P2Y(1) or M1 receptors in Xenopus oocytes elicited a characteristic inwardly rectifying current without receptor stimulation. This current displayed distinct activation and inactivation kinetics and was highly Ca(2+...     »
Zeitschriftentitel:
Biochem Biophys Res Commun
Jahr:
2004
Band / Volume:
322
Heft / Issue:
1
Seitenangaben Beitrag:
177-85
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.bbrc.2004.07.103
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/15313189
Print-ISSN:
0006-291X
TUM Einrichtung:
Urologische Klinik und Poliklinik
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