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- Titel:
Antibacterial effects of extracorporeal shock waves.
- Dokumenttyp:
- Evaluation Studies; Journal Article; Article
- Autor(en):
- Gerdesmeyer, L; von Eiff, C; Horn, C; Henne, M; Roessner, M; Diehl, P; Gollwitzer, H
- Abstract:
- Despite considerable knowledge about effects of extracorporeal shock-wave therapy (ESWT) on eukaryotic tissues, only little data are available concerning their effect on prokaryotic microorganisms. The objective of the present study was to determine the bactericidal activity as a function of energy flux density and shock-wave impulse number. Standardised suspensions of Staphylococcus aureus ATCC 25923 were exposed to different impulse numbers of shock waves with an energy flux density (ED) up to 0.96 mJ mm(-2) (2 Hz). Subsequently, viable bacteria were quantified by culture and compared with an untreated control. After applying 4000 impulses, a significant bactericidal effect was observed with a threshold ED of 0.59 mJ mm(-2) (p < 0.05). A threshold impulse number of more than 1000 impulses was necessary to reduce bacterial growth (p < 0.05). Further elevation of energy and impulse number exponentially increased bacterial killing. ESWT proved to exert significant antibacterial effect in an energy-dependent manner. Certain types of difficult-to-treat infections could offer new applications for ESWT.
- Zeitschriftentitel:
- Ultrasound Med Biol
- Jahr:
- 2005
- Band / Volume:
- 31
- Heft / Issue:
- 1
- Seitenangaben Beitrag:
- 115-9
- Sprache:
- eng
- Volltext / DOI:
- doi:10.1016/j.ultrasmedbio.2004.08.022
- PubMed:
- http://view.ncbi.nlm.nih.gov/pubmed/15653238
- Print-ISSN:
- 0301-5629
- TUM Einrichtung:
- Klinik und Poliklinik für Orthopädie und Sportorthopädie
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