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Title:

Neurotrophin-mediated rapid signaling in the central nervous system: mechanisms and functions.

Document type:
Journal Article; Review; Review
Author(s):
Blum, R; Konnerth, A
Abstract:
Neurotrophins regulate growth, survival, and differentiation of central neurons. In addition to the "classical" effects that are relatively slow neurotrophins also elicit rapid signaling that modulates a variety of cellular functions such as membrane excitability, synaptic transmission, and activity-dependent synaptic plasticity. These rapid actions are mediated mainly through the interaction of Trk receptors with ion channels and ionotropic receptors in the plasma membrane.
Journal title abbreviation:
Physiology (Bethesda)
Year:
2005
Journal volume:
20
Pages contribution:
70-8
Language:
eng
Fulltext / DOI:
doi:10.1152/physiol.00042.2004
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/15653842
Print-ISSN:
1548-9213
TUM Institution:
Institut für Neurowissenschaften
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