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- Title:
Cortical calcium waves in resting newborn mice.
- Document type:
- Journal Article; Article
- Author(s):
- Adelsberger, H; Garaschuk, O; Konnerth, A
- Abstract:
- Using a new optical fiber-based approach, we demonstrate the presence of recurrent Ca(2+) transients in cortical neurons of non-anesthetized newborn mice in vivo. These Ca(2+) waves reflect the correlated activity of thousands of cells and were detected only in resting, but not in moving pups. Our results suggest that Ca(2+)-dependent cortical maturation occurs predominantly during the intermittent sleep-like resting periods that are characteristic for the first days of postnatal life.
- Journal title abbreviation:
- Nat Neurosci
- Year:
- 2005
- Journal volume:
- 8
- Journal issue:
- 8
- Pages contribution:
- 988-90
- Language:
- eng
- Fulltext / DOI:
- doi:10.1038/nn1502
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/16007081
- Print-ISSN:
- 1097-6256
- TUM Institution:
- Institut für Neurowissenschaften
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