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Title:

Cortical calcium waves in resting newborn mice.

Document type:
Journal Article; Article
Author(s):
Adelsberger, H; Garaschuk, O; Konnerth, A
Abstract:
Using a new optical fiber-based approach, we demonstrate the presence of recurrent Ca(2+) transients in cortical neurons of non-anesthetized newborn mice in vivo. These Ca(2+) waves reflect the correlated activity of thousands of cells and were detected only in resting, but not in moving pups. Our results suggest that Ca(2+)-dependent cortical maturation occurs predominantly during the intermittent sleep-like resting periods that are characteristic for the first days of postnatal life.
Journal title abbreviation:
Nat Neurosci
Year:
2005
Journal volume:
8
Journal issue:
8
Pages contribution:
988-90
Language:
eng
Fulltext / DOI:
doi:10.1038/nn1502
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/16007081
Print-ISSN:
1097-6256
TUM Institution:
Institut für Neurowissenschaften
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