Cortical calcium waves in resting newborn mice.

Titel:: Cortical calcium waves in resting newborn mice.
Dokumenttyp:: Journal Article; Article
Autor(en):: Adelsberger, H; Garaschuk, O; Konnerth, A
Abstract:: Using a new optical fiber-based approach, we demonstrate the presence of recurrent Ca(2+) transients in cortical neurons of non-anesthetized newborn mice in vivo. These Ca(2+) waves reflect the correlated activity of thousands of cells and were detected only in resting, but not in moving pups. Our results suggest that Ca(2+)-dependent cortical maturation occurs predominantly during the intermittent sleep-like resting periods that are characteristic for the first days of postnatal life.
Zeitschriftentitel:: Nat Neurosci
Jahr:: 2005
Band / Volume:: 8
Heft / Issue:: 8
Seitenangaben Beitrag:: 988-90
Sprache:: eng
Volltext / DOI:: doi:10.1038/nn1502
PubMed:: http://view.ncbi.nlm.nih.gov/pubmed/16007081
Print-ISSN:: 1097-6256
TUM Einrichtung:: Institut für Neurowissenschaften
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